Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen
نویسندگان
چکیده
منابع مشابه
Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen
Allorecognition is the activation of the adaptive immune system to foreign human leukocyte antigen (HLA) resulting in the generation of alloantibodies. Due to a high polymorphism, foreign HLA is recognized by the immune system following transplant, transfusion, or pregnancy resulting in the formation of the germinal center and the generation of long-lived alloantibody-producing memory B cells. ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2016
ISSN: 1664-3224
DOI: 10.3389/fimmu.2016.00030